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Cambridge Healthtech Institute’s 2nd Annual

Deep Sequencing and Single Cell Analysis for Antibody Discovery
( 抗体発見のためのディープシーケンシングと単一細胞解析 )

Best Practices and Technologies for Applying Repertoire Analysis to the Discovery of Therapeutic Proteins

1月23日~24日

Part of the Protein Engineering & Development pipeline

The rapid adoption of deep sequencing and single B cell analysis has given discovery scientists an extraordinary view into human and animal immune repertoires that is now informing all aspects of biopharmaceutical R&D. This dynamic field is bringing together the disciplines of immunology, structural and computational biology, informatics, and microfluidics to offer previously unimaginable perspectives that will drive discovery of the next generation of biologic drugs. PepTalk’s 2nd Annual Deep Sequencing and Single Cell Analysis for Antibody Discovery conference explores new science and technology in this field and how these advanced capabilities are being implemented and integrated with platforms, workflows, and traditional discovery methods.

Preliminary Agenda

KEYNOTE PRESENTATION: Talk Title to be Announced

Bryan Briney, PhD, Assistant Professor, Immunology and Microbiology, The Scripps Research Institute

ANTIBODY DISCOVERY APPLICATIONS

Combining Novel Single Cell Imaging, Culture and NGS Technologies to Optimize the Lead Generation Process

Elke Glasmacher, PhD, Head, Immunobiology, Roche, Germany

Deep Sequencing Analysis of Phage Selection Outputs: Leaving Conventional Screening Behind

Stefan Ewert, PhD, Senior Investigator, Novartis Pharma AG, Switzerland

Single Cell Assays for Difficult Targets

Navin Varadarajan, PhD, Associate Professor, Chemical and Biomolecular Engineering, University of Houston

RAPID SCREENING AND MACHINE LEARNING

Combining Single Cell TCR Sequencing and Transcriptomics to Discover Tumor Specific T Cells by Unsupervised Learning

Alexander Yermanos, Researcher, Biosystems Science and Engineering, ETH Zurich, Switzerland

NGS-Enabled Synthetic Ab Discovery

Jarrett Adams, PhD, Associate Director, Toronto Recombinant Antibody Center, Canada

Long Read Next Generation Sequencing and Machine Learning for Antibody Discovery

Andrew Bradbury, PhD, MB BS (MD), CSO, Specifica, Inc.

High-Throughput Functional Screening of Antibody Libraries

Ryan Kelly, PhD, Research Scientist, xCella Biosciences

The Antaeus Platform: Single Cell Screens Based on DNA Polymerase Fusions to Report on Functional Antibody–Antigen Interactions at High Throughput

Jimmy Gollihar, PhD, Researcher, Center for Systems and Synthetic Biology, University of Texas at Austin

NEXT GENERATION APPLICATIONS

Integrating Repertoire Display Technology into a Target Agnostic Discovery Platform

Sean Carroll, PhD, Associate Director, Molecular Biology, Atreca

Single Cell Droplet Microfluidics for Discovery of Therapeutic Antibodies

Aude Segaliny, PhD, Group Leader, Assay Biology & Scientific Liaison, Amberstone Biosciences

Talk Title to be Announced

Vu Truong, PhD, CSO & CEO, R&D, Aridis Pharmaceuticals, Inc.



* 不測の事態により、事前の予告なしにプログラムが変更される場合があります。

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