研修セミナー

2019年3月14-15日 | Hilton San Francisco Union Square

今度の学会では、技能の習得に重点を置いた研修セミナーが新たに加わります。研修セミナーでは、メインプログラムやシンポジウム、プレカンファレンスワークショップでは取り上げることのできないレベルまで特定のテーマを深く掘り下げる講座が設定されており、トピックも研究面や事業面に焦点を絞り込んだものや、個人の能力開発を目的としたものなど多様性に富んでいます。


TS1: ポイントオブケア診断についての基本的な手引き
Holger Becker, PhD, Founder & CSO, microfluidic ChipShop GmbH
This 1.5-day lecture-based interactive seminar will provide an overview on the technological aspects of POC system developments. It will introduce current technologies such as microfluidics, sensors, paper- and smartphone-based approaches and discuss their trends and limitations. It will present a variety of POC systems in different stages of their development, from early stage to established diagnostic systems in the clinical routine. Market aspects of POC systems as well as practical examples of commercialization for molecular diagnostic, immunological and clinical tests will be presented.

TS2: 低分子薬創薬開発入門
H. James Harwood Jr., PhD, Founder and CEO, Delphi BioMedical Consultants, LLC
This 1.5-day lecture-based interactive seminar focuses on strategies for identifying drug discovery targets, discovering and characterizing small molecule hits, and developing structure-activity relationships to advance hits through lead optimization, preclinical development, and clinical evaluation. Participants will learn the stages and processes required to advance programs from idea to clinic, through examples and case studies. This seminar is intended for scientists in either academia or industry who would like to become more familiar with small molecule drug discovery and development.

TS3: 臨床次世代シーケンシングラボラトリー総論
Jamie Platt, PhD, Managing Director, BRIDGenomics, LLC
Nearly 10 years after the first publication of next-generation sequencing, this paradigm shifting technology has progressively migrated into the clinical diagnostic space. A diversity of clinical diagnostic assays is now routinely performed on a variety of NGS platforms, spanning from single gene to multi-gene sequencing, to genome wide analyses for the detection of germline and somatic mutations. For clinical laboratories with NGS experience, and especially for those just starting to use the technology, designing and operationalizing robust NGS assays remains a challenge. This Training Seminar will review principles and diagnostic approaches for NGS assays as applied to molecular oncology and inherited disorders, platforms and instruments, as well as laboratory accreditation and proficiency testing specific to NGS.

TS4: リキッドバイオプシー入門
Stuart S. Martin, PhD, Professor, Physiology, Marlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine
This 1.5-day lecture-based interactive seminar will provide an introduction to the biology and science of liquid biopsies. It will provide an in-depth look into the clinical application, utility and validation of liquid biopsy assays with a focus on how to choose the right assay for your goals. It will present a variety of liquid biopsy techniques and go into the pros and cons of each. Overall, this seminar will provide attendees with a comprehensive tool-kit to overcome their liquid biopsy challenges.

TS5: デジタルパソロジー向け画像解析およびディープラーニング入門
Kate Lillard Tunstall, PhD, CSO, Indica Labs, Inc.
Doug Bowman, Director of Pharma Services, Indica Labs, Inc.                                                
This training seminar will include both hands-on and lecture components designed to introduce basic digital pathology image analysis and deep learning concepts to histopathology and pathology professionals who have had limited previous exposure. In the first part of the seminar, we will cover digital pathology image analysis concepts, staining and imaging requirements, post-analysis data interpretation, typical applications and case studies. We will then take a shallow dive into deep learning in pathology and introduce you to some of the basic terminology, concepts and methods which are relevant to the pathologist’s workflow. Researchers currently using deep learning will discuss applications and clinical utility. The seminar will wrap up with a hands-on workshop (laptop required).

TS6: 非侵襲的な医学診断:資金調達、新たなデバイスの開発と商業化

Eric Sugalski, President, Smithwise

Novel diagnostic devices are a critical part of the rapidly evolving health technology landscape. Wearable systems are tracking long-term patient data that aid in delivery of new therapies. Handheld devices are capturing vitals and offering patients and providers information needed to treat chronic diseases. While technology is rapidly evolving, so are the clinical, regulatory, reimbursement and business factors that more often define the success and failure of new ventures. This workshop will introduce the key topics that are crucial for early stage innovators to understand in validating clinical needs, converging on potential solutions, and developing devices with an eye toward commercialization. Case studies and hands-on activities will be used to interactively work through the challenges facing new diagnostic ventures and the strategies that will optimize business success.

TS7: 前臨床研究のための統計的思考

Katherine Giacoletti, Partner, SynoloStats LLC

Tara Scherder, Partner, SynoloStats LLC

A number of recent publications have highlighted the challenges of reproducibility in science, including opportunities for increasing the effectiveness of preclinical development studies by leveraging statistical concepts and practices. In this seminar, participants will learn a variety of statistical analysis methods relevant to preclinical development, emphasizing the use of statistical thinking and understanding variability to explore and make inferences from data. The benefits of statistically designed experiments will be clear, and several critical study design elements will be described, including: power and sample size, some useful study designs, randomization, standardizing measurements, maximizing the information from an experiment, and sound techniques for analysis. The complexities and solutions for small data sets will also be discussed. Participants will learn from a combination of lecture, case studies, and practicing the application of concepts with realistic examples.

TS8: 自己免疫疾患と癌治療薬創薬のための免疫学入門

Tim Bauler, PhD, Assistant Professor, Department of Biomedical Sciences, Western Michigan University Homer Stryker M.D. School of Medicine

Tom Sundberg, PhD, Group Leader, Cellular Pharmacology, Broad Institute of MIT and Harvard

This 1.5-day training seminar will provide an introduction to human immunology for discovery pharmacologists, biologists and chemists working in the biopharmaceutical industry on inflammation, autoimmune, or immune-oncology programs. This training seminar will focus on how the immune system is organized and gives rise to both normal and pathogenic immune responses. This overview will also serve as a basis for discussions of how the immune system can be modulated through biopharmaceutical intervention to either suppress pathogenic inflammation or enhance anti-tumor immunity.




What is a Training Seminar?
Each Training Seminar offers 1.5 Days of instruction with start and stop times for each day shown above and on the Event-at-a-Glance published in the onsite Program & Event Guide. Training Seminars will include morning and afternoon refreshment breaks, as applicable, and lunch will be provided to all registered attendees on the full day of the class.

Each person registered specifically for the training seminar will be provided with a hard copy handbook for the seminar in which they are registered. A limited number of additional handbooks will be available for other delegates who wish to attend the seminar, but after these have been distributed no additional books will be available.

Though CHI encourages track and symposia hopping between conference programs, we ask that Training Seminars not be disturbed once they have begun. In the interest of maintaining the highest quality learning environment for Training Seminar attendees, and because Seminars are conducted differently than conference programming, we ask that attendees commit to attending the entire program, and NOT engaging in track hopping, as to not disturb the hands-on style instruction being offered to the other participants.

* 不測の事態により、事前の予告なしにプログラムが変更される場合があります。

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